Cyclical Chromatin Looping and Transcription Factor Association on the Regulatory Regions of the p21 (CDKN1A) Gene in Response to 1α,25-Dihydroxyvitamin D(3)

The nuclear receptor vitamin D receptor (VDR) is known to associate with three vitamin D response element (VDREs)-containing regions within the CDKN1A (p21) gene region. Here we show in MDA-MB453 breast cancer cells that the natural VDR ligand 1α,25-dihydroxyvitamin D(3) causes cyclical transcriptio...

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Main Authors: Saramäki, Anna, Diermeier, Sarah, Kellner, Ruth, Laitinen, Heidi, Vaïsänen, Sami, Carlberg, Carsten
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Transcription, Chromatin, and Epigenetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658101/
https://ncbi.nlm.nih.gov/pubmed/19122196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808090200
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