Distinct HDACs regulate the transcriptional response of human cyclin-dependent kinase inhibitor genes to trichostatin A and 1α,25-dihydroxyvitamin D(3)

The anti-proliferative effects of histone deacetylase (HDAC) inhibitors and 1α,25-dihydroxyvitamin D(3) [1α,25(OH)(2)D(3)] converge via the interaction of un-liganded vitamin D receptor (VDR) with co-repressors recruiting multiprotein complexes containing HDACs and via the induction of cyclin-depend...

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Detalhes bibliográficos
Main Authors: Malinen, Marjo, Saramäki, Anna, Ropponen, Antti, Degenhardt, Tatjana, Väisänen, Sami, Carlberg, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248733/
https://ncbi.nlm.nih.gov/pubmed/17999998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm913
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