Selective use of multiple vitamin D response elements underlies the 1 α,25-dihydroxyvitamin D(3)-mediated negative regulation of the human CYP27B1 gene

The human 25-hydroxyvitamin D(3) (25(OH)D(3)) 1α-hydroxylase, which is encoded by the CYP27B1 gene, catalyzes the metabolic activation of the 25(OH)D(3) into 1α,25-dihydroxyvitamin D(3) (1α,25(OH)(2)D(3)), the most biologically potent vitamin D(3) metabolite. The most important regulator of CYP27B1...

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Bibliographic Details
Main Authors: Turunen, Mikko M., Dunlop, Thomas W., Carlberg, Carsten, Väisänen, Sami
Format: Artigo
Language:Inglês
Published: Oxford University Press 2007
Subjects:
Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885674/
https://ncbi.nlm.nih.gov/pubmed/17426122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm179
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