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Chromatin acetylation at transcription start sites and vitamin D receptor binding regions relates to effects of 1α,25-dihydroxyvitamin D(3) and histone deacetylase inhibitors on gene expression

The nuclear hormone 1α,25-dihydroxyvitamin D(3) (1α,25(OH)(2)D(3) or 1,25D) regulates its target genes via activation of the transcription factor vitamin D receptor (VDR) far more specifically than the chromatin modifier trichostatin A (TsA) via its inhibitory action on histone deacetylases. We sele...

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Detalhes bibliográficos
Main Authors: Seuter, Sabine, Heikkinen, Sami, Carlberg, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592476/
https://ncbi.nlm.nih.gov/pubmed/23093607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks959
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