Acetylation of FoxO1 Activates Bim Expression to Induce Apoptosis in Response to Histone Deacetylase Inhibitor Depsipeptide Treatment

Histone deacetylase (HDAC) inhibitors have been shown to induce cell cycle arrest and apoptosis in cancer cells. However, the mechanisms of HDAC inhibitor induced apoptosis are incompletely understood. In this study, depsipeptide, a novel HDAC inhibitor, was shown to be able to induce significant ap...

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Detalhes bibliográficos
Main Authors: Yang, Yang, Zhao, Ying, Liao, Wenjuan, Yang, Jing, Wu, Lipeng, Zheng, Zhixing, Yu, Yu, Zhou, Wen, Li, Lian, Feng, Jingnan, Wang, Haiying, Zhu, Wei-Guo
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657887/
https://ncbi.nlm.nih.gov/pubmed/19308286
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