Acetylation of FoxO1 Activates Bim Expression to Induce Apoptosis in Response to Histone Deacetylase Inhibitor Depsipeptide Treatment

Histone deacetylase (HDAC) inhibitors have been shown to induce cell cycle arrest and apoptosis in cancer cells. However, the mechanisms of HDAC inhibitor induced apoptosis are incompletely understood. In this study, depsipeptide, a novel HDAC inhibitor, was shown to be able to induce significant ap...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yang, Yang, Zhao, Ying, Liao, Wenjuan, Yang, Jing, Wu, Lipeng, Zheng, Zhixing, Yu, Yu, Zhou, Wen, Li, Lian, Feng, Jingnan, Wang, Haiying, Zhu, Wei-Guo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Neoplasia Press Inc. 2009
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657887/
https://ncbi.nlm.nih.gov/pubmed/19308286
Tagiau: Ychwanegu Tag
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