Transition from Nonspecific to Specific DNA Interactions along the Substrate-Recognition Pathway of Dam Methyltransferase

DNA methyltransferases methylate target bases within specific nucleotide sequences. Three structures are described for bacteriophage T4 DNA-adenine methyltransferase (T4Dam) in ternary complexes with partially and fully specific DNA and a methyl-donor analog. We also report the effects of substituti...

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Bibliographic Details
Main Authors:	Horton, John R., Liebert, Kirsten, Hattman, Stanley, Jeltsch, Albert, Cheng, Xiaodong
Format:	Artigo
Language:	Inglês
Published:	2005
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2656680/ https://ncbi.nlm.nih.gov/pubmed/15882618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2005.02.021
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Transition from Nonspecific to Specific DNA Interactions along the Substrate-Recognition Pathway of Dam Methyltransferase

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