A dual role for substrate S-adenosyl-l-methionine in the methylation reaction with bacteriophage T4 Dam DNA-[N6-adenine]-methyltransferase

The fluorescence of 2-aminopurine ((2)A)-substituted duplexes (contained in the GATC target site) was investigated by titration with T4 Dam DNA-(N6-adenine)-methyltransferase. With an unmethylated target ((2)A/A duplex) or its methylated derivative ((2)A/(m)A duplex), T4 Dam produced up to a 50-fold...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Malygin, Ernst G., Evdokimov, Alexey A., Zinoviev, Victor V., Ovechkina, Lidiya G., Lindstrom, William M., Reich, Norbert O., Schlagman, Samuel L., Hattman, Stanley
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55703/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11376154/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.11.2361
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