Repurposing epigenetic inhibitors to target the Clostridioides difficile-specific DNA adenine methyltransferase and sporulation regulator CamA

Epigenetically targeted therapeutic development, particularly for SAM-dependent methylations of DNA, mRNA and histones has been proceeding rapidly for cancer treatments over the past few years. However, this approach has barely begun to be exploited for developing new antibiotics, despite an overwhe...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Jujun Zhou, John R. Horton, Dan Yu, Ren Ren, Robert M. Blumenthal, Xing Zhang, Xiaodong Cheng
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Taylor & Francis Group 2022-09-01
Σειρά:	Epigenetics
Θέματα:	s-adenosyl-l-methionine analogues dot1l inhibitors prmt inhibitors pseudomembranous colitis
Διαθέσιμο Online:	http://dx.doi.org/10.1080/15592294.2021.1976910
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