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Substrate Specificity of the HEMK2 Protein Glutamine Methyltransferase and Identification of Novel Substrates

Bacterial HEMK2 homologs initially had been proposed to be involved in heme biogenesis or to function as adenine DNA methyltransferase. Later it was shown that this family of enzymes has protein glutamine methyltransferase activity, and they methylate the glutamine residue in the GGQ motif of riboso...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kusevic, Denis, Kudithipudi, Srikanth, Jeltsch, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813560/
https://ncbi.nlm.nih.gov/pubmed/26797129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.711952
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