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Investigation of the methylation of Numb by the SET8 protein lysine methyltransferase

It has been reported that the Numb protein is methylated at lysine 158 and 163 and that this methylation is introduced by the SET8 protein lysine methyltransferase [Dhami et al., (2013) Molecular Cell 50, 565–576]. We studied this methylation in vitro using peptide arrays and recombinant Numb protei...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Weirich, Sara, Kusevic, Denis, Kudithipudi, Srikanth, Jeltsch, Albert
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585732/
https://ncbi.nlm.nih.gov/pubmed/26391684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13813
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