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Investigation of the methylation of Numb by the SET8 protein lysine methyltransferase

It has been reported that the Numb protein is methylated at lysine 158 and 163 and that this methylation is introduced by the SET8 protein lysine methyltransferase [Dhami et al., (2013) Molecular Cell 50, 565–576]. We studied this methylation in vitro using peptide arrays and recombinant Numb protei...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Weirich, Sara, Kusevic, Denis, Kudithipudi, Srikanth, Jeltsch, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585732/
https://ncbi.nlm.nih.gov/pubmed/26391684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13813
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