Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation

Obesity promotes insulin resistance and chronic inflammation. Disrupting any of several distinct steps in lipid synthesis decreases adiposity, but it is unclear if this approach coordinately corrects the environment that propagates metabolic disease. We tested the hypothesis that inactivation of FAS...

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Библиографические подробности
Главные авторы: Chakravarthy, Manu V., Zhu, Yimin, Yin, Li, Coleman, Trey, Pappan, Kirk L., Marshall, Connie A., McDaniel, Michael L., Semenkovich, Clay F.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2009
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656656/
https://ncbi.nlm.nih.gov/pubmed/19029118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800379-JLR200
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