Defective regulation of POMC precedes hypothalamic inflammation in diet-induced obesity

Obesity is the result of a long-term positive energy balance in which caloric intake overrides energy expenditure. This anabolic state results from the defective activity of hypothalamic neurons involved in the sensing and response to adiposity. However, it is currently unknown what the earliest obe...

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發表在:Sci Rep
Main Authors: Souza, Gabriela F. P., Solon, Carina, Nascimento, Lucas F., De-Lima-Junior, Jose C., Nogueira, Guilherme, Moura, Rodrigo, Rocha, Guilherme Z., Fioravante, Milena, Bobbo, Vanessa, Morari, Joseane, Razolli, Daniela, Araujo, Eliana P., Velloso, Licio A.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931679/
https://ncbi.nlm.nih.gov/pubmed/27373214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29290
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