Defective regulation of POMC precedes hypothalamic inflammation in diet-induced obesity

Obesity is the result of a long-term positive energy balance in which caloric intake overrides energy expenditure. This anabolic state results from the defective activity of hypothalamic neurons involved in the sensing and response to adiposity. However, it is currently unknown what the earliest obe...

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I publikationen:Sci Rep
Huvudupphovsmän: Souza, Gabriela F. P., Solon, Carina, Nascimento, Lucas F., De-Lima-Junior, Jose C., Nogueira, Guilherme, Moura, Rodrigo, Rocha, Guilherme Z., Fioravante, Milena, Bobbo, Vanessa, Morari, Joseane, Razolli, Daniela, Araujo, Eliana P., Velloso, Licio A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931679/
https://ncbi.nlm.nih.gov/pubmed/27373214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29290
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