Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation

Obesity promotes insulin resistance and chronic inflammation. Disrupting any of several distinct steps in lipid synthesis decreases adiposity, but it is unclear if this approach coordinately corrects the environment that propagates metabolic disease. We tested the hypothesis that inactivation of FAS...

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Autors principals: Chakravarthy, Manu V., Zhu, Yimin, Yin, Li, Coleman, Trey, Pappan, Kirk L., Marshall, Connie A., McDaniel, Michael L., Semenkovich, Clay F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656656/
https://ncbi.nlm.nih.gov/pubmed/19029118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800379-JLR200
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