Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation

Obesity promotes insulin resistance and chronic inflammation. Disrupting any of several distinct steps in lipid synthesis decreases adiposity, but it is unclear if this approach coordinately corrects the environment that propagates metabolic disease. We tested the hypothesis that inactivation of FAS...

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Détails bibliographiques
Auteurs principaux: Chakravarthy, Manu V., Zhu, Yimin, Yin, Li, Coleman, Trey, Pappan, Kirk L., Marshall, Connie A., McDaniel, Michael L., Semenkovich, Clay F.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656656/
https://ncbi.nlm.nih.gov/pubmed/19029118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800379-JLR200
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