Decreased Fetal Size Is Associated With β-Cell Hyperfunction in Early Life and Failure With Age

OBJECTIVE—Low birth weight is associated with diabetes in adult life. Accelerated or “catch-up” postnatal growth in response to small birth size is thought to presage disease years later. Whether adult disease is caused by intrauterine β-cell–specific programming or by altered metabolism associated...

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Autors principals: Chakravarthy, Manu V., Zhu, Yimin, Wice, Mitchell B., Coleman, Trey, Pappan, Kirk L., Marshall, Connie A., McDaniel, Michael L., Semenkovich, Clay F.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2008
Matèries:
Islet Studies
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551680/
https://ncbi.nlm.nih.gov/pubmed/18591393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0404
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