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Brain fatty acid synthase activates PPARα to maintain energy homeostasis
Central nervous system control of energy balance affects susceptibility to obesity and diabetes, but how fatty acids, malonyl-CoA, and other metabolites act at this site to alter metabolism is poorly understood. Pharmacological inhibition of fatty acid synthase (FAS), rate limiting for de novo lipog...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1937501/ https://ncbi.nlm.nih.gov/pubmed/17694178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31183 |
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