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Nutrient-dependent phosphorylation channels lipid synthesis to regulate PPARα

Peroxisome proliferator-activated receptor (PPAR)α is a nuclear receptor that coordinates liver metabolism during fasting. Fatty acid synthase (FAS) is an enzyme that stores excess calories as fat during feeding, but it also activates hepatic PPARα by promoting synthesis of an endogenous ligand. Her...

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Detalles Bibliográficos
Main Authors: Jensen-Urstad, Anne P. L., Song, Haowei, Lodhi, Irfan J., Funai, Katsuhiko, Yin, Li, Coleman, Trey, Semenkovich, Clay F.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679387/
https://ncbi.nlm.nih.gov/pubmed/23585690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M036103
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