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Selective Down-Regulation of Nuclear Poly(ADP-Ribose) Glycohydrolase
BACKGROUND: The formation of ADP-ribose polymers on target proteins by poly(ADP-ribose) polymerases serves a variety of cell signaling functions. In addition, extensive activation of poly(ADP-ribose) polymerase-1 (PARP-1) is a dominant cause of cell death in ischemia-reperfusion, trauma, and other c...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2655720/ https://ncbi.nlm.nih.gov/pubmed/19319190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004896 |
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