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Phosphodiesterase 4 and Phosphatase 2A Differentially Regulate cAMP/Protein Kinase A Signaling for Cardiac Myocyte Contraction under Stimulation of β(1) Adrenergic Receptor

Activation of the β adrenergic receptor (βAR) induces a tightly controlled cAMP/protein kinase A (PKA) activity to ensure an agonist dose-dependent and saturable contraction response in animal heart. We have found that stimulation of β(1)AR by isoproterenol induces maximal contraction responses at t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: De Arcangelis, Vania, Soto, Dagoberto, Xiang, Yang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654611/
https://ncbi.nlm.nih.gov/pubmed/18703669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.049718
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