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Regulation of TLR4-mediated signaling by IBP/Def6, a novel activator of Rho GTPases

TLRs play a fundamental role in innate immune responses. Although Rho GTPases have been implicated in TLR-mediated signaling pathways, the molecules that control their activation in response to TLR engagement are largely unknown. IFN regulatory factor-4-binding protein (IBP; which is encoded by the...

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Bibliografiske detaljer
Main Authors: Chen, Qinzhong, Gupta, Sanjay, Pernis, Alessandra B.
Format: Artigo
Sprog:Inglês
Udgivet: The Society for Leukocyte Biology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653944/
https://ncbi.nlm.nih.gov/pubmed/19074553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0308219
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