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Population Pharmacokinetics of Cyclophosphamide and Metabolites in Children with Neuroblastoma: a Report from the Children’s Oncology Group

Cyclophosphamide-based regimens are front-line treatment for numerous pediatric malignancies, however current dosing methods result in considerable interpatient variability in tumor response and toxicity. In this pediatric population, our objectives were to 1. quantify and explain the pharmacokineti...

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Detalhes bibliográficos
Main Authors: McCune, Jeannine S., Salinger, David H., Vicini, Paolo, Oglesby, Celeste, Blough, David K., Park, Julie R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652687/
https://ncbi.nlm.nih.gov/pubmed/18927240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0091270008325928
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