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POPULATION PHARMACOKINETIC/DYNAMIC MODEL OF LYMPHOSUPPRESSION AFTER FLUDARABINE ADMINISTRATION
PURPOSE: Quantitative relationships between 9-β-D-arabinofuranosyl-2-fluoroadenine (F-ara-A) concentrations and lymphosuppression have not been reported, but would be useful for regimen design. A population pharmacokinetic/pharmacodynamic model was constructed in this study using data from 41 hemato...
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Publié dans: | Cancer Chemother Pharmacol |
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Auteurs principaux: | , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
2014
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4282607/ https://ncbi.nlm.nih.gov/pubmed/25374408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-014-2618-2 |
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