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A Limited Sampling Schedule to Estimate Mycophenolic Acid Area Under the Concentration-Time Curve in Hematopoietic Cell Transplantation Recipients

Mycophenolate mofetil (MMF) is a key component of post-grafting immunosuppression in hematopoietic cell transplant (HCT) recipients. The plasma area under the curve (AUC) of its active metabolite, mycophenolic acid (MPA), is associated with MMF efficacy and toxicity. This study developed a populatio...

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Bibliografiske detaljer
Main Authors: Li, Hong, Mager, Donald E., Bemer, Meagan J., Salinger, David H., Vicini, Paolo, Sandmaier, Brenda M., Nash, Richard, McCune, Jeannine S.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309163/
https://ncbi.nlm.nih.gov/pubmed/22174435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0091270011429567
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