Phase II Randomized Comparison of Topotecan Plus Cyclophosphamide Versus Topotecan Alone in Children With Recurrent or Refractory Neuroblastoma: A Children's Oncology Group Study

PURPOSE: Single-agent topotecan (TOPO) and combination topotecan and cyclophosphamide (TOPO/CTX) were compared in a phase II randomized trial in relapsed/refractory neuroblastoma. Because responders often underwent further therapies, novel statistical methods were required to compare the long-term o...

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Detalhes bibliográficos
Main Authors: London, Wendy B., Frantz, Christopher N., Campbell, Laura A., Seeger, Robert C., Brumback, Babette A., Cohn, Susan L., Matthay, Katherine K., Castleberry, Robert P., Diller, Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2010
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940398/
https://ncbi.nlm.nih.gov/pubmed/20660830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.27.5016
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