Phase I Study of Decitabine with Doxorubicin and Cyclophosphamide in Children with Neuroblastoma and Other Solid Tumors: A Children’s Oncology Group Study

BACKGROUND: Demethylating agents may alter the expression of genes involved in chemotherapy resistance. We conducted a phase I trial to determine the toxicity and molecular effects of the demethylating agent, decitabine, followed by doxorubicin and cyclophosphamide in children with refractory solid...

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Autores principales: George, Rani E., Lahti, Jill M., Adamson, Peter C., Zhu, Kejin, Finkelstein, David, Ingle, A. Mark, Reid, Joel M., Krailo, Mark, Neuberg, Donna, Blaney, Susan M., Diller, Lisa
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025700/
https://ncbi.nlm.nih.gov/pubmed/20589651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.22607
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