Llwytho...

TORC-specific phosphorylation of mTOR: phospho-Ser2481 is a marker for intact mTORC2

The mammalian target of rapamycin (mTOR) Ser/Thr kinase is the catalytic component of two evolutionarily conserved signaling complexes. mTOR signaling complex 1 (mTORC1) is a key regulator of growth factor and nutrient signaling. S6 kinase (S6K) is the best characterized downstream effector of mTORC...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Copp, Jeremy, Manning, Gerard, Hunter, Tony
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652681/
https://ncbi.nlm.nih.gov/pubmed/19244117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3014
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