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TORC-specific phosphorylation of mTOR: phospho-Ser2481 is a marker for intact mTORC2
The mammalian target of rapamycin (mTOR) Ser/Thr kinase is the catalytic component of two evolutionarily conserved signaling complexes. mTOR signaling complex 1 (mTORC1) is a key regulator of growth factor and nutrient signaling. S6 kinase (S6K) is the best characterized downstream effector of mTORC...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2652681/ https://ncbi.nlm.nih.gov/pubmed/19244117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3014 |
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