Phosphorylation of mTOR Ser2481 is a key target limiting the efficacy of rapalogs for treating hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Although recent studies facilitate the identification of crucial genes and relevant regulatory pathways, therapeutic approaches against advanced HCC are insufficiently effective. Therefore, we aimed here to develop potent th...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Watari, Kosuke, Nishitani, Ayumi, Shibata, Tomohiro, Noda, Masaki, Kawahara, Akihiko, Akiba, Jun, Murakami, Yuichi, Yano, Hirohisa, Kuwano, Michihiko, Ono, Mayumi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216950/
https://ncbi.nlm.nih.gov/pubmed/27329724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10161
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