Oncogenic Y‐box binding protein‐1 as an effective therapeutic target in drug‐resistant cancer

af Kuwano, Michihiko, Shibata, Tomohiro, Watari, Kosuke, Ono, Mayumi
Udgivet i Cancer Sci (2019)

Phosphorylation of mTOR Ser2481 is a key target limiting the efficacy of rapalogs for treating hepatocellular carcinoma

af Watari, Kosuke, Nishitani, Ayumi, Shibata, Tomohiro, Noda, Masaki, Kawahara, Akihiko, Akiba, Jun, Murakami, Yuichi, Yano, Hirohisa, Kuwano, Michihiko, Ono, Mayumi
Udgivet i Oncotarget (2016)

N-myc Downstream-regulated Gene 1 Promotes Tumor Inflammatory Angiogenesis through JNK Activation and Autocrine Loop of Interleukin-1α by Human Gastric Cancer Cells

af Murakami, Yuichi, Watari, Kosuke, Shibata, Tomohiro, Uba, Manami, Ureshino, Hiroki, Kawahara, Akihiko, Abe, Hideyuki, Izumi, Hiroto, Mukaida, Naofumi, Kuwano, Michihiko, Ono, Mayumi
Udgivet 2013

FGFR1 activation is an escape mechanism in human lung cancer cells resistant to afatinib, a pan-EGFR family kinase inhibitor

af Azuma, Koichi, Kawahara, Akihiko, Sonoda, Kahori, Nakashima, Kazutaka, Tashiro, Kousuke, Watari, Kosuke, Izumi, Hiroto, Kage, Masayoshi, Kuwano, Michihiko, Ono, Mayumi, Hoshino, Tomoaki
Udgivet 2014

Impaired differentiation of macrophage lineage cells attenuates bone remodeling and inflammatory angiogenesis in Ndrg1 deficient mice

af Watari, Kosuke, Shibata, Tomohiro, Nabeshima, Hiroshi, Shinoda, Ai, Fukunaga, Yuichi, Kawahara, Akihiko, Karasuyama, Kazuyuki, Fukushi, Jun-ichi, Iwamoto, Yukihide, Kuwano, Michihiko, Ono, Mayumi
Udgivet i Sci Rep (2016)

N-myc Downstream Regulated Gene 1 (NDRG1) Promotes Metastasis of Human Scirrhous Gastric Cancer Cells through Epithelial Mesenchymal Transition

af Ureshino, Hiroki, Murakami, Yuichi, Watari, Kosuke, Izumi, Hiroto, Kawahara, Akihiko, Kage, Masayoshi, Arao, Tokuzo, Nishio, Kazuto, Yanagihara, Kazuyoshi, Kinoshita, Hisafumi, Kuwano, Michihiko, Ono, Mayumi
Udgivet 2012

Y-box binding protein YBX1 and its correlated genes as biomarkers for poor outcomes in patients with breast cancer

af Shibata, Tomohiro, Tokunaga, Eriko, Hattori, Satoshi, Watari, Kosuke, Murakami, Yuichi, Yamashita, Nami, Oki, Eiji, Itou, Junji, Toi, Masakazu, Maehara, Yoshihiko, Kuwano, Michihiko, Ono, Mayumi
Udgivet i Oncotarget (2018)

NDRG1 activates VEGF-A-induced angiogenesis through PLCγ1/ERK signaling in mouse vascular endothelial cells

af Watari, Kosuke, Shibata, Tomohiro, Fujita, Hideaki, Shinoda, Ai, Murakami, Yuichi, Abe, Hideyuki, Kawahara, Akihiko, Ito, Hiroshi, Akiba, Jun, Yoshida, Shigeo, Kuwano, Michihiko, Ono, Mayumi
Udgivet i Commun Biol (2020)

The augmented expression of the cytidine deaminase gene by 5-azacytidine predicts therapeutic efficacy in myelodysplastic syndromes

af Murakami, Yuichi, Kimura, Yoshizo, Kawahara, Akihiko, Mitsuyasu, Shohei, Miyake, Hidetoshi, Tohyama, Kaoru, Endo, Yoshio, Yoshida, Nao, Imamura, Yutaka, Watari, Kosuke, Ono, Mayumi, Okamura, Takashi, Kuwano, Michihiko
Udgivet i Oncotarget (2019)

Nuclear expression of N-myc downstream regulated gene 1/Ca(2+)-associated protein 43 is closely correlated with tumor angiogenesis and poor survival in patients with gastric cancer

af KAWAHARA, AKIHIKO, AKIBA, JUN, HATTORI, SATOSHI, YAMAGUCHI, TOMOHIKO, ABE, HIDEYUKI, TAIRA, TOMOKI, URESHINO, HIROKI, MURAKAMI, YUICHI, WATARI, KOSUKE, KOUFUJI, KIKUO, SHIROUZU, KAZUO, KUWANO, MICHIHIKO, ONO, MAYUMI, KAGE, MASAYOSHI
Udgivet 2011

Tumor-Derived Interleukin-1 Promotes Lymphangiogenesis and Lymph Node Metastasis through M2-Type Macrophages

af Watari, Kosuke, Shibata, Tomohiro, Kawahara, Akihiko, Sata, Ken-ichi, Nabeshima, Hiroshi, Shinoda, Ai, Abe, Hideyuki, Azuma, Koichi, Murakami, Yuichi, Izumi, Hiroto, Takahashi, Takashi, Kage, Masayoshi, Kuwano, Michihiko, Ono, Mayumi
Udgivet 2014

The activation of SRC family kinases and focal adhesion kinase with the loss of the amplified, mutated EGFR gene contributes to the resistance to afatinib, erlotinib and osimertini...

af Murakami, Yuichi, Sonoda, Kahori, Abe, Hideyuki, Watari, Kosuke, Kusakabe, Daiki, Azuma, Koichi, Kawahara, Akihiko, Akiba, Jun, Oneyama, Chitose, Pachter, Jonathan A., Sakai, Kazuko, Nishio, Kazuto, Kuwano, Michihiko, Ono, Mayumi
Udgivet i Oncotarget (2017)

Selective Covalent Targeting of Mutated EGFR(T790M) with Chlorofluoroacetamide-Pyrimidines

af Sato, Mami, Fuchida, Hirokazu, Shindo, Naoya, Kuwata, Keiko, Tokunaga, Keisuke, Xiao-Lin, Guo, Inamori, Ryo, Hosokawa, Keitaro, Watari, Kosuke, Shibata, Tomohiro, Matsunaga, Naoya, Koyanagi, Satoru, Ohdo, Shigehiro, Ono, Mayumi, Ojida, Akio
Udgivet i ACS Med Chem Lett (2020)

Macrophage Infiltration Predicts a Poor Prognosis for Human Ewing Sarcoma

af Fujiwara, Toshifumi, Fukushi, Jun-ichi, Yamamoto, Shunsaku, Matsumoto, Yoshihiro, Setsu, Nokitaka, Oda, Yoshinao, Yamada, Hisakata, Okada, Seiji, Watari, Kosuke, Ono, Mayumi, Kuwano, Michihiko, Kamura, Satoshi, Iida, Keiichiro, Okada, Yuko, Koga, Mihoko, Iwamoto, Yukihide
Udgivet 2011