Oncogenic Y‐box binding protein‐1 as an effective therapeutic target in drug‐resistant cancer

по Kuwano, Michihiko, Shibata, Tomohiro, Watari, Kosuke, Ono, Mayumi
Опубликовано в: Cancer Sci (2019)

Phosphorylation of mTOR Ser2481 is a key target limiting the efficacy of rapalogs for treating hepatocellular carcinoma

по Watari, Kosuke, Nishitani, Ayumi, Shibata, Tomohiro, Noda, Masaki, Kawahara, Akihiko, Akiba, Jun, Murakami, Yuichi, Yano, Hirohisa, Kuwano, Michihiko, Ono, Mayumi
Опубликовано в: Oncotarget (2016)

N-myc Downstream-regulated Gene 1 Promotes Tumor Inflammatory Angiogenesis through JNK Activation and Autocrine Loop of Interleukin-1α by Human Gastric Cancer Cells

по Murakami, Yuichi, Watari, Kosuke, Shibata, Tomohiro, Uba, Manami, Ureshino, Hiroki, Kawahara, Akihiko, Abe, Hideyuki, Izumi, Hiroto, Mukaida, Naofumi, Kuwano, Michihiko, Ono, Mayumi
Опубликовано 2013

FGFR1 activation is an escape mechanism in human lung cancer cells resistant to afatinib, a pan-EGFR family kinase inhibitor

по Azuma, Koichi, Kawahara, Akihiko, Sonoda, Kahori, Nakashima, Kazutaka, Tashiro, Kousuke, Watari, Kosuke, Izumi, Hiroto, Kage, Masayoshi, Kuwano, Michihiko, Ono, Mayumi, Hoshino, Tomoaki
Опубликовано 2014

Impaired differentiation of macrophage lineage cells attenuates bone remodeling and inflammatory angiogenesis in Ndrg1 deficient mice

по Watari, Kosuke, Shibata, Tomohiro, Nabeshima, Hiroshi, Shinoda, Ai, Fukunaga, Yuichi, Kawahara, Akihiko, Karasuyama, Kazuyuki, Fukushi, Jun-ichi, Iwamoto, Yukihide, Kuwano, Michihiko, Ono, Mayumi
Опубликовано в: Sci Rep (2016)

N-myc Downstream Regulated Gene 1 (NDRG1) Promotes Metastasis of Human Scirrhous Gastric Cancer Cells through Epithelial Mesenchymal Transition

по Ureshino, Hiroki, Murakami, Yuichi, Watari, Kosuke, Izumi, Hiroto, Kawahara, Akihiko, Kage, Masayoshi, Arao, Tokuzo, Nishio, Kazuto, Yanagihara, Kazuyoshi, Kinoshita, Hisafumi, Kuwano, Michihiko, Ono, Mayumi
Опубликовано 2012

Y-box binding protein YBX1 and its correlated genes as biomarkers for poor outcomes in patients with breast cancer

по Shibata, Tomohiro, Tokunaga, Eriko, Hattori, Satoshi, Watari, Kosuke, Murakami, Yuichi, Yamashita, Nami, Oki, Eiji, Itou, Junji, Toi, Masakazu, Maehara, Yoshihiko, Kuwano, Michihiko, Ono, Mayumi
Опубликовано в: Oncotarget (2018)

NDRG1 activates VEGF-A-induced angiogenesis through PLCγ1/ERK signaling in mouse vascular endothelial cells

по Watari, Kosuke, Shibata, Tomohiro, Fujita, Hideaki, Shinoda, Ai, Murakami, Yuichi, Abe, Hideyuki, Kawahara, Akihiko, Ito, Hiroshi, Akiba, Jun, Yoshida, Shigeo, Kuwano, Michihiko, Ono, Mayumi
Опубликовано в: Commun Biol (2020)

The augmented expression of the cytidine deaminase gene by 5-azacytidine predicts therapeutic efficacy in myelodysplastic syndromes

по Murakami, Yuichi, Kimura, Yoshizo, Kawahara, Akihiko, Mitsuyasu, Shohei, Miyake, Hidetoshi, Tohyama, Kaoru, Endo, Yoshio, Yoshida, Nao, Imamura, Yutaka, Watari, Kosuke, Ono, Mayumi, Okamura, Takashi, Kuwano, Michihiko
Опубликовано в: Oncotarget (2019)

Nuclear expression of N-myc downstream regulated gene 1/Ca(2+)-associated protein 43 is closely correlated with tumor angiogenesis and poor survival in patients with gastric cancer

по KAWAHARA, AKIHIKO, AKIBA, JUN, HATTORI, SATOSHI, YAMAGUCHI, TOMOHIKO, ABE, HIDEYUKI, TAIRA, TOMOKI, URESHINO, HIROKI, MURAKAMI, YUICHI, WATARI, KOSUKE, KOUFUJI, KIKUO, SHIROUZU, KAZUO, KUWANO, MICHIHIKO, ONO, MAYUMI, KAGE, MASAYOSHI
Опубликовано 2011

Tumor-Derived Interleukin-1 Promotes Lymphangiogenesis and Lymph Node Metastasis through M2-Type Macrophages

по Watari, Kosuke, Shibata, Tomohiro, Kawahara, Akihiko, Sata, Ken-ichi, Nabeshima, Hiroshi, Shinoda, Ai, Abe, Hideyuki, Azuma, Koichi, Murakami, Yuichi, Izumi, Hiroto, Takahashi, Takashi, Kage, Masayoshi, Kuwano, Michihiko, Ono, Mayumi
Опубликовано 2014

The activation of SRC family kinases and focal adhesion kinase with the loss of the amplified, mutated EGFR gene contributes to the resistance to afatinib, erlotinib and osimertini...

по Murakami, Yuichi, Sonoda, Kahori, Abe, Hideyuki, Watari, Kosuke, Kusakabe, Daiki, Azuma, Koichi, Kawahara, Akihiko, Akiba, Jun, Oneyama, Chitose, Pachter, Jonathan A., Sakai, Kazuko, Nishio, Kazuto, Kuwano, Michihiko, Ono, Mayumi
Опубликовано в: Oncotarget (2017)

Selective Covalent Targeting of Mutated EGFR(T790M) with Chlorofluoroacetamide-Pyrimidines

по Sato, Mami, Fuchida, Hirokazu, Shindo, Naoya, Kuwata, Keiko, Tokunaga, Keisuke, Xiao-Lin, Guo, Inamori, Ryo, Hosokawa, Keitaro, Watari, Kosuke, Shibata, Tomohiro, Matsunaga, Naoya, Koyanagi, Satoru, Ohdo, Shigehiro, Ono, Mayumi, Ojida, Akio
Опубликовано в: ACS Med Chem Lett (2020)

Macrophage Infiltration Predicts a Poor Prognosis for Human Ewing Sarcoma

по Fujiwara, Toshifumi, Fukushi, Jun-ichi, Yamamoto, Shunsaku, Matsumoto, Yoshihiro, Setsu, Nokitaka, Oda, Yoshinao, Yamada, Hisakata, Okada, Seiji, Watari, Kosuke, Ono, Mayumi, Kuwano, Michihiko, Kamura, Satoshi, Iida, Keiichiro, Okada, Yuko, Koga, Mihoko, Iwamoto, Yukihide
Опубликовано 2011