Phosphorylation of mTOR Ser2481 is a key target limiting the efficacy of rapalogs for treating hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Although recent studies facilitate the identification of crucial genes and relevant regulatory pathways, therapeutic approaches against advanced HCC are insufficiently effective. Therefore, we aimed here to develop potent th...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Watari, Kosuke, Nishitani, Ayumi, Shibata, Tomohiro, Noda, Masaki, Kawahara, Akihiko, Akiba, Jun, Murakami, Yuichi, Yano, Hirohisa, Kuwano, Michihiko, Ono, Mayumi
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216950/
https://ncbi.nlm.nih.gov/pubmed/27329724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10161
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