טוען...
Abnormal Brain Iron Homeostasis in Human and Animal Prion Disorders
Neurotoxicity in all prion disorders is believed to result from the accumulation of PrP-scrapie (PrP(Sc)), a β-sheet rich isoform of a normal cell-surface glycoprotein, the prion protein (PrP(C)). Limited reports suggest imbalance of brain iron homeostasis as a significant associated cause of neurot...
שמור ב:
| Main Authors: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2009
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2652663/ https://ncbi.nlm.nih.gov/pubmed/19283067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000336 |
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