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Cyst Formation in Kidney via B-Raf Signaling in the PKD2 Transgenic Mice

The pathogenic mechanisms of human autosomal dominant polycystic kidney disease (ADPKD) have been well known to include the mutational inactivation of PKD2. Although haploinsufficiency and loss of heterozygosity at the Pkd2 locus can cause cyst formation in mice, polycystin-2 is frequently expressed...

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書誌詳細
主要な著者: Park, Eun Young, Sung, Young Hoon, Yang, Moon Hee, Noh, Ji Yeun, Park, So Young, Lee, Tae Young, Yook, Yeon Joo, Yoo, Kyung Hyun, Roh, Kyung Jin, Kim, Ingyu, Hwang, Young-Hwan, Oh, Goo Taeg, Seong, Je Kyung, Ahn, Curie, Lee, Han-Woong, Park, Jong Hoon
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652279/
https://ncbi.nlm.nih.gov/pubmed/19098310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805890200
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