Autophagy induction promotes renal cyst growth in polycystic kidney disease

BACKGROUND: Polycystic kidney disease (PKD) involves renal cysts arising from proliferating tubular cells. Autophagy has been recently suggested as a potential therapeutic target in PKD, and mammalian target of rapamycin (mTOR) is a key negative regulator of autophagy. However, the effect of autopha...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:EBioMedicine
मुख्य लेखकों: Lee, Eun Ji, Ko, Je Yeong, Oh, Sumin, Jun, Jaehee, Mun, Hyowon, Lim, Chae Ji, Seo, Seungwoon, Ko, Hyuk Wan, Kim, Hyunho, Oh, Yun Kyu, Ahn, Curie, Kang, Minyong, Kim, Min Jung, Yoo, Kyung Hyun, Oh, Goo Taeg, Park, Jong Hoon
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2020
विषय:
Research Paper
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501056/
https://ncbi.nlm.nih.gov/pubmed/32949996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102986
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