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Autophagy induction promotes renal cyst growth in polycystic kidney disease
BACKGROUND: Polycystic kidney disease (PKD) involves renal cysts arising from proliferating tubular cells. Autophagy has been recently suggested as a potential therapeutic target in PKD, and mammalian target of rapamycin (mTOR) is a key negative regulator of autophagy. However, the effect of autopha...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | EBioMedicine |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Elsevier
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7501056/ https://ncbi.nlm.nih.gov/pubmed/32949996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102986 |
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