Autophagy induction promotes renal cyst growth in polycystic kidney disease

BACKGROUND: Polycystic kidney disease (PKD) involves renal cysts arising from proliferating tubular cells. Autophagy has been recently suggested as a potential therapeutic target in PKD, and mammalian target of rapamycin (mTOR) is a key negative regulator of autophagy. However, the effect of autopha...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:EBioMedicine
Päätekijät: Lee, Eun Ji, Ko, Je Yeong, Oh, Sumin, Jun, Jaehee, Mun, Hyowon, Lim, Chae Ji, Seo, Seungwoon, Ko, Hyuk Wan, Kim, Hyunho, Oh, Yun Kyu, Ahn, Curie, Kang, Minyong, Kim, Min Jung, Yoo, Kyung Hyun, Oh, Goo Taeg, Park, Jong Hoon
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2020
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501056/
https://ncbi.nlm.nih.gov/pubmed/32949996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102986
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