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Cyst formation in the PKD2 (1-703) transgenic rat precedes deregulation of proliferation-related pathways

BACKGROUND: Polycystic Kidney Disease is characterized by the formation of large fluid-filled cysts that eventually destroy the renal parenchyma leading to end-stage renal failure. Although remarkable progress has been made in understanding the pathologic mechanism of the disease, the precise orches...

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Detalhes bibliográficos
Main Authors: Koupepidou, Panayiota, Felekkis, Kyriacos N, Kränzlin, Bettina, Sticht, Carsten, Gretz, Norbert, Deltas, Constantinos
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936873/
https://ncbi.nlm.nih.gov/pubmed/20813037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-11-23
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