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Widespread balancing selection and pathogen-driven selection at blood group antigen genes

Historically, allelic variations in blood group antigen (BGA) genes have been regarded as possible susceptibility factors for infectious diseases. Since host–pathogen interactions are major determinants in evolution, BGAs can be thought of as selection targets. In order to verify this hypothesis, we...

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Detalhes bibliográficos
Main Authors: Fumagalli, Matteo, Cagliani, Rachele, Pozzoli, Uberto, Riva, Stefania, Comi, Giacomo P., Menozzi, Giorgia, Bresolin, Nereo, Sironi, Manuela
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652214/
https://ncbi.nlm.nih.gov/pubmed/18997004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.082768.108
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