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Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions
Many human genes have adapted to the constant threat of exposure to infectious agents; according to the “hygiene hypothesis,” lack of exposure to parasites in modern settings results in immune imbalances, augmenting susceptibility to the development of autoimmune and allergic conditions. Here, by es...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715056/ https://ncbi.nlm.nih.gov/pubmed/19468064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082779 |
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