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The signature of long-standing balancing selection at the human defensin β-1 promoter
BACKGROUND: Defensins, small endogenous peptides with antimicrobial activity, are pivotal components of the innate immune response. A large cluster of defensin genes is located on human chromosome 8p; among them the beta defensin 1 (DEFB1) promoterhas been extensively studied since discovery that sp...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2592704/ https://ncbi.nlm.nih.gov/pubmed/18817538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2008-9-9-r143 |
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