Widespread balancing selection and pathogen-driven selection at blood group antigen genes

Historically, allelic variations in blood group antigen (BGA) genes have been regarded as possible susceptibility factors for infectious diseases. Since host–pathogen interactions are major determinants in evolution, BGAs can be thought of as selection targets. In order to verify this hypothesis, we...

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Библиографические подробности
Главные авторы: Fumagalli, Matteo, Cagliani, Rachele, Pozzoli, Uberto, Riva, Stefania, Comi, Giacomo P., Menozzi, Giorgia, Bresolin, Nereo, Sironi, Manuela
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2009
Предметы:
Letter
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652214/
https://ncbi.nlm.nih.gov/pubmed/18997004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.082768.108
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