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Widespread balancing selection and pathogen-driven selection at blood group antigen genes

Historically, allelic variations in blood group antigen (BGA) genes have been regarded as possible susceptibility factors for infectious diseases. Since host–pathogen interactions are major determinants in evolution, BGAs can be thought of as selection targets. In order to verify this hypothesis, we...

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Main Authors: Fumagalli, Matteo, Cagliani, Rachele, Pozzoli, Uberto, Riva, Stefania, Comi, Giacomo P., Menozzi, Giorgia, Bresolin, Nereo, Sironi, Manuela
פורמט: Artigo
שפה:Inglês
יצא לאור: Cold Spring Harbor Laboratory Press 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652214/
https://ncbi.nlm.nih.gov/pubmed/18997004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.082768.108
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