Sequencing human–gibbon breakpoints of synteny reveals mosaic new insertions at rearrangement sites

The gibbon genome exhibits extensive karyotypic diversity with an increased rate of chromosomal rearrangements during evolution. In an effort to understand the mechanistic origin and implications of these rearrangement events, we sequenced 24 synteny breakpoint regions in the white-cheeked gibbon (N...

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Bibliografske podrobnosti
Main Authors: Girirajan, Santhosh, Chen, Lin, Graves, Tina, Marques-Bonet, Tomas, Ventura, Mario, Fronick, Catrina, Fulton, Lucinda, Rocchi, Mariano, Fulton, Robert S., Wilson, Richard K., Mardis, Elaine R., Eichler, Evan E.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2009
Teme:
Letter
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652201/
https://ncbi.nlm.nih.gov/pubmed/19029537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.086041.108
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