Sequencing human–gibbon breakpoints of synteny reveals mosaic new insertions at rearrangement sites

The gibbon genome exhibits extensive karyotypic diversity with an increased rate of chromosomal rearrangements during evolution. In an effort to understand the mechanistic origin and implications of these rearrangement events, we sequenced 24 synteny breakpoint regions in the white-cheeked gibbon (N...

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Bibliografiske detaljer
Main Authors: Girirajan, Santhosh, Chen, Lin, Graves, Tina, Marques-Bonet, Tomas, Ventura, Mario, Fronick, Catrina, Fulton, Lucinda, Rocchi, Mariano, Fulton, Robert S., Wilson, Richard K., Mardis, Elaine R., Eichler, Evan E.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2009
Fag:
Letter
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652201/
https://ncbi.nlm.nih.gov/pubmed/19029537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.086041.108
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