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Sequencing human–gibbon breakpoints of synteny reveals mosaic new insertions at rearrangement sites

The gibbon genome exhibits extensive karyotypic diversity with an increased rate of chromosomal rearrangements during evolution. In an effort to understand the mechanistic origin and implications of these rearrangement events, we sequenced 24 synteny breakpoint regions in the white-cheeked gibbon (N...

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Detalhes bibliográficos
Main Authors: Girirajan, Santhosh, Chen, Lin, Graves, Tina, Marques-Bonet, Tomas, Ventura, Mario, Fronick, Catrina, Fulton, Lucinda, Rocchi, Mariano, Fulton, Robert S., Wilson, Richard K., Mardis, Elaine R., Eichler, Evan E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652201/
https://ncbi.nlm.nih.gov/pubmed/19029537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.086041.108
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