Sequencing human–gibbon breakpoints of synteny reveals mosaic new insertions at rearrangement sites

The gibbon genome exhibits extensive karyotypic diversity with an increased rate of chromosomal rearrangements during evolution. In an effort to understand the mechanistic origin and implications of these rearrangement events, we sequenced 24 synteny breakpoint regions in the white-cheeked gibbon (N...

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Detalles Bibliográficos
Autores principales: Girirajan, Santhosh, Chen, Lin, Graves, Tina, Marques-Bonet, Tomas, Ventura, Mario, Fronick, Catrina, Fulton, Lucinda, Rocchi, Mariano, Fulton, Robert S., Wilson, Richard K., Mardis, Elaine R., Eichler, Evan E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2009
Materias:
Letter
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652201/
https://ncbi.nlm.nih.gov/pubmed/19029537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.086041.108
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