Structural and biochemical characterization of MepR, a multidrug binding transcription regulator of the Staphylococcus aureus multidrug efflux pump MepA

MepR is a multidrug binding transcription regulator that represses expression of the Staphylococcus aureus multidrug efflux pump gene, mepA, as well as its own gene. MepR is induced by multiple cationic toxins, which are also substrates of MepA. In order to understand the gene regulatory and drug-bi...

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Hlavní autoři: Kumaraswami, Muthiah, Schuman, Jason T., Seo, Susan M., Kaatz, Glenn W., Brennan, Richard G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
Structural Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651776/
https://ncbi.nlm.nih.gov/pubmed/19129225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn1046
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