Functional Consequences of Substitution Mutations in MepR, a Repressor of the Staphylococcus aureus mepA Multidrug Efflux Pump Gene

The expression of mepA, encoding the Staphylococcus aureus MepA multidrug efflux protein, is repressed by the MarR homologue MepR. MepR dimers bind differently to operators upstream of mepR and mepA, with affinity being greatest at the mepA operator. MepR substitution mutations may result in mepA ov...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schindler, Bryan D., Seo, Susan M., Jacinto, Pauline L., Kumaraswami, Muthiah, Birukou, Ivan, Brennan, Richard G., Kaatz, Glenn W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2013
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754585/
https://ncbi.nlm.nih.gov/pubmed/23749979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00565-13
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