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Mutagenesis and Modeling To Predict Structural and Functional Characteristics of the Staphylococcus aureus MepA Multidrug Efflux Pump

MepA is a multidrug and toxin extrusion (MATE) family protein and the only MATE protein encoded within the Staphylococcus aureus genome. Structural data for MATE proteins are limited to a single high-resolution example, NorM of Vibrio cholerae. Substitution mutations were created in MepA using gradi...

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Detalhes bibliográficos
Main Authors: Schindler, Bryan D., Patel, Diixa, Seo, Susan M., Kaatz, Glenn W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554018/
https://ncbi.nlm.nih.gov/pubmed/23175649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01679-12
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