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Claudin-3 gene silencing with siRNA suppresses ovarian tumor growth and metastasis
Claudin-3 (CLDN3) is a tight junction protein that is overexpressed in 90% of ovarian tumors. Previous in vitro studies have indicated that CLDN3 overexpression promotes the migration, invasion, and survival of ovarian cancer cells. Here, we investigated the efficacy of lipidoid-formulated CLDN3 siR...
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| Huvudupphovsmän: | , , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651300/ https://ncbi.nlm.nih.gov/pubmed/19208807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813348106 |
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