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GIV is a nonreceptor GEF for Gαi with a unique motif that regulates Akt signaling
Heterotrimeric G proteins are molecular switches that control signal transduction. Ligand-occupied, G protein-coupled receptors serve as the canonical guanine nucleotide exchange factors (GEFs) that activate heterotrimeric G proteins. A few unrelated nonreceptor GEFs have also been described, but li...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651282/ https://ncbi.nlm.nih.gov/pubmed/19211784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900294106 |
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