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Mutations at embB Codon 306 Are an Important Molecular Indicator of Ethambutol Resistance in Mycobacterium tuberculosis

Ethambutol resistance in clinical Mycobacterium tuberculosis isolates is associated primarily with missense mutations in the embB gene. However, recent reports have described the presence of embB mutations, especially those at embB codon 306, in isolates susceptible to ethambutol. To clarify the rol...

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Main Authors: Starks, Angela M., Gumusboga, Aysel, Plikaytis, Bonnie B., Shinnick, Thomas M., Posey, James E.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650568/
https://ncbi.nlm.nih.gov/pubmed/19104018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01357-08
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